I don't have CFS but I have noticed in a few artciles that Methylcobalamin B12 is mentioned for CFS... just wondered if any of you had try this. It may be worth looking into if not. You can read the full article here:

health101.org/art_methylcobalamin.htm

"There's a buzz over B12 these days for two reasons, one scientific and the other economic. First, the science: Over the last decade or so, researchers have strongly implicated the toxic amino acid homocysteine in a variety of disease states. Homocysteine tends to accumulate in the body whenever B12 gets deficient, and this accumulation has been linked with increased risk of Alzheimer's disease1,2, cardiovascular disease3, chronic fatigue syndrome/fibromyalgia4 and multiple sclerosis5 among other conditions."

Hi Bushi,
I use B12, Folic Acid and glutathione.
I was in very rough shape and came across Dr. Grace Ziem's chemical injury web site.
She suggests in her protocol to self inject/and or nebulize these three.
I purchased an Areoneb medical nebulizer and then got my naturopath to write me a prescription for "preservative free" methylcobalamin, glutathione, Folic acid.
It gave me my brain back and then some. I had a lifelong undiagnosed learning disorder that is now absent and most brain fog is gone for the first time. (unless I am inundated with chemicals). My chronic abdominal pain has mostly subsided as well.

So I use it daily, usually 2x or more - injections and nebulize depending on how I am feeling.

All the best!

Juniper:)

Hi guys,

I have also self-injected with methylcobalamin for a number of reasons 1. I have small intestinal bacterial and yeast overgrowth and these interfere with B12 absorption 2. I have homozygous SNPs for vital methylation cycle genes that ensure the body is able to methylate "regular" B12.

Both of these problems are common in people with CFS and make B12 and methyl-B12 in particular very important. The methylation cycle, in which methyl-B12 is a lynch pin, is vital for detoxification, neurotransmitter synthesis, DNA/RNA synthesis, and a host of other vital functions.

We have lots of articles here at EiR about methylcobalamin and CFS. Just search using the Google search box at the very top right of any page.

Great to hear you are having such success with the Grace Ziem protocol Juniper

Thanks for highlighting the topic Bushi!

I also found this article that explains how it can help with IBS symptoms and that symptoms a B12 deficiency can be mistaken for IBS:

www.livestrong.com/article/474388-the-re...amin-b12-deficiency/

I'm currently taking 5,000mcg (5mg) Methylcobalamin three times a day in tablet form under the tongue. This is quite a lot from what I can gather. However, as it's a water soluble vitamin it shouldn't be too dangerous. My body should just expel what it doesn't need.

I'm hoping that this may help with my IBS-D symptoms somehow.

For those of you who don't know the vitamins you need to be careful with are the fat soluble ones such as: vitamins, A, D, E & K. (just thought I'd throw that out there).

Bushi - Have you investigated at all the hydroxocobalamin form of B-12?

My limited understanding is that this form is typically used with the B12 injections, but is produced by a few companies in sublingual form.

Hi, I've been take B-12 in tablet form. I don't know if I have low levels of it but as I don't really digest food at all I thought my nervous system and 'B' levels may have been compromised over the years so I thought I'd take it for a couple of months. I bought my stash from Health Monthly UK