http://www.ei-resource.org/ 2258-419 http://www.ei-resource.org/treatment-%11-nutritional-supplements/nutrients-s%11z/same-(s%11adenosyl-methionine)/ I count myself very lucky to have discovered SAM-e after having suffered from a form of depression for around 5 years that included a total lack of motivation and enjoyment in life. I was for all intents and purposes a zombie - a shell of a man. My doctor fed me every antidepressant med going including SSRIs (Prozac & Zoloft), SNRIs (Venlafaxine) and even an MAOI (Parnate) and none produced any notable improvement. Eventually I began looking into supplements and after a few failures with St. Johns Wort and other herbs I decided to see a nutritionist. My nutritionist said the symptoms of my depression sounded like I had a deficiency of dopamine and/or norepinephrine so she suggested I try phenylalanine (an amino acid from which these are made). This produced a small but noticeable improvement. When I reported this she gave me SAM-e and - wow! After a week on 400mg per day I was really feeling like myself again for the first time in years. I actually felt like getting off my ass and doing things and the enjoyment in even the little things in life returned! After a few months on 400mg I did notice I was becoming a bit too stimulated (which can be a common side-effect apparently) so I cut back to 300mg a day and have stuck to that without a problem for a year now. SAM-e is quite expensive compared to other supplements but if you suffer from symptoms similar to what I have described then I would definitely say try it - it could be the key to getting your life back. ]]> Mon, 26 Oct 2009 22:26:20 +0000