High Dose Vitamin D Therapy for Seasonal Affective Disorder (S.A.D.)
Posted by: Maff
on Jan 23, 2009
As part of my illness I have suffered greatly with Seasonal Affective Disorder, known also by its appropriate acronym - SAD. I notice large seasonal variations in my mood, energy levels and other symptoms and also day to day variations depending on the weather. Even a cloudy or rainy day in summer can make me feel depressed and sluggish.
I have recently tried high dose vitamin D treatment after seeing studies that showed very positive results and wanted to tell you about what it has done for me. First though I want to talk a bit about my experience with SAD.
There was a time before I knew about SAD and realised I had it when I felt suicidal each year from October to March. All I felt was total despair and spent most of my time in bed. If I hadn't still been living at home with my parents I wouldn't have been able to cope and who knows what would have happened. As it was I stubbornly fought a mental battle against thoughts of ending my life and managed to pull through.
Thankfully after a few years I saw the pattern and realised what was going on. The first treatment I heard about for SAD was bright light therapy. This is usually one of the first treatments recommended by doctors (along with antidepressant medication) and involves sitting in front of a special 'light box' for a certain period of time each day, usually 30 minutes to 2 hours depending on the light box and severity of the patient's symptoms. Light boxes are designed to provide light bright enough to mimic the effects the sun has on the body; namely suppressing production of the sleep hormone melatonin and stimulating production of the mood enhancing neurotransmitter serotonin (along with a number of others).
» Learn more about SAD light boxes
Unfortunately for me, although studies suggest light boxes are very effective as a treatment for SAD and I heard many sufferers recommening them, they did little to reduce my symptoms. I experienced a moderate energizing effect but my mood was still very low.
The first thing that really made a difference for me was the simple measure of waking up earlier in winter. My sleep pattern had been to go to bed about 2-3am and wake up at 12-1pm (a shift common in ME/CFS, SAD and other environmental illnesses). One year as October approached I began going to bed between 11pm and midnight and waking up at 9am. The difference this made to my mood was astonishing. Although during that winter there was still a noticeable difference to how I felt in summer I no longer felt the heavy weight of despair and didn't have a single suicidal thought. Further to this getting outside during daylight hours in winter and letting the suns rays directly enter the eye also made a positive difference.
So if you suffer from SAD and spend your days in bed asleep or with the curtains closed try waking up earlier and getting outside as much as possible. Like me you may be amazed by how much your mood improves.
Now on to vitamin D. The sun not only affects the physiology of our bodies (and our mood) by the action of bright light hitting the retina of the eye but also by triggering the production of vitamin D in the skin as its rays strike uncovered areas. You may be surprised to learn that "vitamin D" is actually not a vitamin at all; its active form is actually a form of steroid hormone. As a result it has powerful effects on the body beyond aiding in the absorption of calcium and prevention of osteoporosis for which it has traditionally been known. The thing that is important to SAD sufferers is that vitamin D is required for the production and activation of the mood elevating neurotransmitters serotonin, dopamine and noradrenaline/norepinephrine.
When exposed to certain wavelengths of UVB rays from the sun the skin produces vitamin D3 (cholecalciferol). This is the most active form and is also found in oily fish and animal products. Plants contain the vitamin D2 (ergocalciferol) form which is less well absorbed and utilised by the body. Vitamin D3 is also widely available in supplement form.
After seeing studies suggesting people low in vitamin D were more likely to develop depression and SAD and that vitamin D supplementation could alleviate the symptoms of SAD I began to suspect it would also benefit me. A few small studies had shown that doses of 800-2000iu per day were enough to help those with SAD so last winter I supplemented 2000iu every day but gained little benefit. However, I then came across research which used much higher doses - 100,000iu in one single dose.
I discussed using higher doses with my nutritionally orientated doctor and she said she had used doses of 25,000-50,000iu D3 per week with her ME/CFS and SAD patients with great success. This works out at roughly 3500-7000iu per day. Vitamin D3 has been shown to be non-toxic at these levels and well tolerated as the body converts it to the active hormone (1,25-dihydroxycholecalciferol) in the liver and kidneys as needed.
I started with a 25,000iu dose and within hours the effects were obvious. My mood, even on an overcast day, was noticeably brighter. It was a strange sensation in that I felt as if it was summer even on a cloudy day in the depths of winter. I found this mood elevation lasted for 3-4 days before starting to really tail off. Taking 50,000iu lasted the maintained the improved mood for the whole week so I now intend to take this dose weekly during the winter.
So it seems I have found the missing piece of my SAD puzzle. The combination of getting as much sunlight as possible and taking high dose vitamin D3 is highly effective at relieving my symptoms and making me feel like I do during the summer months when the sun is doing all of the work.
If you suffer from SAD then I highly recommend you try adding vitamin D3 to your treatment regimen. It may be that 800-2000iu per day may be all you need in which case regular capsules of 1000iu from the healthfood store will be fine. These are very inexpensive. If you require higher doses like myself then getting the concentrated form and taking it weekly or every other week may be a better option. There are a few suppliers on the internet (no prescription required) or you may have to get it through your doctor.
SAD is a terrible thing to experience so I hope this information helps those of you who are suffering.
Here's to brighter and happier winters!
» More on SAD treatment and vitamin D

written by Alan Weber Heath Ohio, February 11, 2009
written by Reiser, June 17, 2009
written by Iowegian, October 14, 2009
Therefore, I happened upon your blog through google search on alternative treatments and it was not much of a decision to give D3 a chance. I have been using it for only two weeks, so I will report back my results at a later date in addition to this post.
I noticed a positive effect with 10,000 IU/day, but it too made me feel very stimulated, so I backed it down to 4,000 IU per day. That seemed to work well for the past two weeks. If fact, I felt almost normal which almost miraculous for me during this time of year. However, yesterday I was very anxious (bad stress headache, loss of sleep, etc.), so I am going to increase the dose to 10,000 IU's again and then plan to back down if the symptoms are under control.
I do have a couple of questions if you do not mind answering.
1. Your blog seems to imply you take your weekly D3 all in one shot. Is that the case and what advantages or disadvantages is there between weekly and daily dosages?
2. My symptoms seem worsen with the advent of weather changes in combination with the lack of sunlight from Fall through late Spring. Do you have a need to adjust your dosages throughout the Winter season as well?
Undecided if D3 will work longterm for me, but I will give it a "go" and report back.
Thanks,
Iowegian
written by hAPPY DAYS, October 18, 2009
Also, try getting to bed by 10pm, at the latest, and rising at 6am (all year round), it makes a huge difference.
I do suffer from SAD and it took years to figure out what the issue was, but this is the first time I've considered using Vitamin D before winter kicks in, just as a precaution.
In the past I've tried St. Johns Wort, which can work for some.
But I have to say that meditation (Viapassana), 2 hours per day, morning and evening, works very effectively. My SAD symptoms disappeared as a result.
written by Craig, January 07, 2010
I ordered some from the United Kingdom stockist and I'm going to try it. I have CFS and IBS and I think also SAD.
Also started on Vitabiotics wellman today
written by Tracey Cardew, September 24, 2010
I've suffered with SAD for about 10 years ago, and my normal winter routine is prophylactic anti-depressants from September to March (along with light therapy, exercise and fresh air). This works fairly well but I hate the side effects of the drugs.
I was really interested by your experience with Vit D3. I've been looking into this since hearing an article on the radio, and after reading your comments I decided to try using Vit D3 instead of my normal antidepressant therapy. From your info and other sources, I decided to start with 5,000 IUs a day. The impact was slight at first and so I increased to 10,000s daily.
Wow - what an effect. I've never felt so 'normal'. Even in the summer a dull day would get me down, but now that the nights are drawing in, I still feel energised and optimistic. I did notice that after about 3 weeks on the high dose I was having trouble sleeping, although this did not leave me feeling tired. Since then I'm taking alternate days of 5,000 and 10,000 units, and I'm considering a 'depot' dose of 50,000 units.
I just want to say thanks for sharing and I hope other sufferers are inspired to try this more natural therapy.
Thanks a million
Tracey
written by Rae, November 01, 2010
written by Timo, November 02, 2010
written by kirsten, November 08, 2010
I've since moved back to the East Coast (US) and am now experiencing the lack of motivation and increased hair loss again. I don't suffer from SAD but was diagnosed with a yeast overgrowth three years ago, so all that you wrote including the adrenal fatigue could be related to candida. Probiotics have helped with the yeast. I use Renew Life 50 Billion strains (for anyone who reads this and needs a good probiotic).
I've been researching hair loss and recently put two and two together about the season change, me not eating dairy, the decreased motivation and Vitamin D. I suspected the Vitamin D was a factor and your article confirms what I was thinking. God bless you for staying with us and sharing your experience to help others.
I will try the D3 and hopefully it will help to slow down/stop my hair loss and help regrow the areas that have thinned out.
One question: would cod liver oil be a good choice for someone who doesn't take gel caps?
All the best,
Kirsten
written by Andra, November 09, 2010
I found your webpage doing a search for vitamin D and SAD, and had a specific question. Do you know about the effectiveness/safety of using Vit D2 instead of D3?
Two other ancillary questions:
*Is there a mobile friendly version of this website? I would love to explore it more, but can only access the internet via my phone. While I did manage to eventually get the article read and submit a comment, it too forever!
*Does anyone else object to the term SAD as I do? I use it, because it fits and people know it. But I do object to the acronym! It is SO MUCH more that "just" being sad!
written by Belle, November 12, 2010
Here's a tough one for you. I am a veggie, with two young children, have PMT and suffer from SAD. My doc keeps trying to put me on anti depressants. I tried them, and they made me feel calmer during my pmt, but i felt so tired and just wanted to sleep all the time. I have now been advised to take them a week before and during my cycle. Again i feel so tired and just want to sleep. This not practical at all with being a single mum of two.
Also sleep deprevated due to a 4 year child who wakes every 3-4 hours during the night.
I was really getting excited and was hoping that D3 was going to solve my problems, when i read that it is animal derived, oh no! I dont eat eggs or fish either. I have made appointment with my doc so was going to ask her for it, but what can i do now ?
Also would you know if Vitamin Bcomplex's help in this regard ?
Thank you again!!
written by Ronda, November 15, 2010
written by Nina, December 11, 2010
I've been a sufferer of SAD for as long as I can remember; I hate it when the Fall/Winter catalogs come out, it's an unpleasant reminder that months of dreary moods and lethargy are just around the corner. Silly, isn't it, how such a little thing is enough to trigger an adverse anticipatory response!
I've been taking 1000 IU of Vit. D daily for the past year or so, strictly to offset the reduced sunlight of our Canadian winters ( I'm a B.C. resident ), but only recently wondered whether an increased dosage would have any positive effects on my mood and energy ( this is how I just discovered your site ).
After reading about your experiences, and going through the testimonials of your commenters, I'm certainly going to give it a shot! Thanks again ..... Nina.
written by Sascha, February 27, 2011
as Vitamin D is stored in the fat cells of the body, i've had the idea that possibly very skinny people might suffer more often from SAD than others. Are you people skinny? (I mean BMI around 20 or lower).
I am and I suffer from SAD. I will try experimenting with D3. My first 25.000 I.U. was kind of weird. Just like an emotional overflow andi didn't know whether to judge good or just strange. The next question is, if you are a skinny person, could it be better to use D3 more frequently than to use high doses? Or is the amoun of fat in the body irrelevant?
However it is, thank you for this thread!




