Chronic Fatigue Syndrome News

Browse our library of news below or learn more about chronic fatigue syndrome (ME/CFS) symptoms, diagnosis and causes.

CFIDS Association launches largest ever chronic fatigue syndrome research initiative

 

The CFIDS Association of America this week announced an unprecedented research initiative with the aim of identifying biomarkers for the disease to improve both diagnosis and treatment.

Following the successful completion of a yearlong, $1 million fundraising campaign, the CFIDS Association of America has announced the recipients of the first grants under their Accelerate CFS Research Initiative.

The research grants totaling $647,940 in funding were awarded to six teams of researchers in the US and Canada who will study a diverse range of factors thought to be involved with the disease process in chronic fatigue syndrome (CFS).

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Study suggests heat shock proteins could provide chronic fatigue syndrome diagnostic test

 

Researchers have discovered differences in levels of an important group of proteins in chronic fatigue syndrome patients which they say could potentially be used as a biomarker to diagnose the condition.

The study published in the latest edition of the journal Clinical and Investigative Medicine suggests that chronic fatigue syndrome (ME/CFS) patients have an abnormal adaptive response to oxidative stress. This means patients are less able to deal with potentially damaging free radicals than healthy people are.

Researchers determined this by comparing levels of heat shock proteins in ME/CFS patients and healthy individuals immediately before and after and up to a week after a standardised treadmill exercise session.

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Chronic fatigue syndrome genetic study links immune dysfunction to loss of thyroid function

 

A recent study study looking at the significance of genes associated with nervous, hormonal and immune abnormalities in chronic fatigue syndrome patients finds a link between them.

For a long time it has been known that both the nervous and endocrine (hormonal) systems are responsible for control of bodily functions and maintaining a state of healthy balance (homeostasis). Over the past few decades it has also become clear that both of these systems are also intimately linked to the immune system and its function.

A new term, "neuroendocrinimmunology" was coined around 20 years ago to describe this connection between the three systems. According to a paper by Reichlin (1993) neuroendocrinimmunology is defined as "the study of neuroendocrine influences on the function of immunocompetent cells", i.e. the influence of the nervous and endocrine systems on immune cells. It also became clear that the communication was a two-way thing however so the subject of neuroendocrinimmunology also includes the way the immune system affects the nervous and endocrine systems.

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Chronic fatigue syndrome linked to HHV-6 central nervous system infection

 

A new study suggests that a low-level central nervous system (CNS) infection could play a role in chronic fatigue syndrome (ME/CFS) particularly in relation to cognitive and mood related symptoms.

The study conducted at Jikei University Medical School in Tokyo, Japan, has identified a novel human herpesvirus-6 (HHV-6) protein present in ME/CFS patients which they did not find in healthy controls. They believe it may contribute to cognitive and psychological symptoms often associated with ME/CFS as well as other chronic illnesses.

Common symptoms of ME/CFS which are most likely to have a direct link to the activity of the HHV-6 virus include poor concentration, short-term memory loss, mental exhaustion and depression.

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High Court review for ME/CFS treatment guidelines in the UK

 

The High Court in London is to hold a judicial review of the current national guidelines for treating Myalgic Encephalomyelitis (M.E.)/Chronic Fatigue Syndrome (CFS) after protests from both patients and the medical profession.

Patients of a devastating illness, Myalgic Encephalomyelitis (M.E.) have today welcomed the news that there is to be a hearing in the High Court in London on the 17th June to decide whether or not to grant permission for a Judicial Review of The National Institute for Health and Clinical Excellence (NICE) guidelines on the illness which is sometimes referred to as Chronic Fatigue Syndrome (CFS) and more recently ME/CFS. NICE is an independent organisation responsible for providing guidelines disease treatment guidelines to doctors in the UK.

NICE issued their Guideline for ME/CFS in August last year amid protests from patients and medical researchers that they had not followed correct protocols in producing the Guideline. Patient groups fear that some patients could be pressured into accepting treatments which at best may be useless and at worst could cause real harm.

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