Pediatr Allergy Immunol. 2008 Jan 16 [Epub ahead of print]

Content of beta-casomorphins in milk of women with a history of allergy.

Sidor K, Jarmołowska B, Kaczmarski M, Kostyra E, Iwan M, Kostyra H. Third Department of Paediatric Diseases, Medical University, Bialystok, Poland.

The prevalence of food allergies increased over the past decade. Most symptoms of food allergy appear during the first 2 yr of life. The aim of this study was to determine the beta-casomorphin-5 and -7 (BCMs) in colostrum and milk of 12 breast-feeding women with a history and clinical manifestation of food allergy. The results were compared with the data obtained from a control group of healthy age-matched breast-feeding women. The level of BCM in women with food allergy was constant during lactation, whereas the highest level of opioid peptides was found in colostrums of healthy women with a subsequent rapid decrease in mature milk. These differences in BCMs profile between allergic and healthy breast-feeding women suggest that BCM content in the human milk may be an indicator of allergic conditions.

PMID: 18208459 [PubMed - as supplied by publisher]

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