Correlation between asthma and irritable bowel syndrome in a general population in Iran in 2003

Respir Med. 2006 Jan;100(1):110-4. Epub 2005 Apr 26.

Correlation between asthma and irritable bowel syndrome in a general population in Iran in 2003.

Amra B, Hoseini-Asl MK, Rahmani AR, Golshan M, Mohamad-Zadeh Z.

Department of Medicine, Pulmonary Unit, Isfahan Medical School, P.O. Box 81655/755, Isfahan, Iran. amra@med.mui.ac.ir

BACKGROUND: Associations have been reported between irritable bowel syndrome (IBS) and asthma. AIMS: To explore the inter-relations between these conditions in a general population sample. SUBJECTS: A randomly selected community sample of 5492 adults. METHODS: All of the subjects were invited for a medical interview. Those subjects suspected to have either asthma and/or IBS underwent spirometry with post-bronchodilator test if indicated. The labeling of subjects as having IBS was based on Rome II criteria. RESULTS: 4762 subjects agreed to take part (86.7% response). Prevalence rates for IBS, and currently active asthma were 7.1% and 3.8%, respectively. Logistic regression showed independent associations between IBS and most asthma symptom categories. There was no significant independent association between IBS and chronic bronchitis. The odds ratio with 95% confidence interval (CI) for IBS and current asthma was 1.79 (1.06-3.03). CONCLUSIONS: These observations indicate the necessity of further community-based studies to elucidate the possible common pathogenic mechanisms involved in two disease entities.

PMID: 16338596 [PubMed - indexed for MEDLINE]

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