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Omega-3 and Omega-6 fatty acids for attention deficit hyperactivity disorder

 

 

 

J Atten Disord. 2009 Mar;12(5):394-401. Epub 2008 Apr 30.

 

Omega-3/omega-6 fatty acids for attention deficit hyperactivity disorder: a randomized placebo-controlled trial in children and adolescents.

 

Johnson M, Ostlund S, Fransson G, Kadesjö B, Gillberg C. Department of Child and Adolescent Psychiatry, Göteborg University, Göteborg, Sweden. This email address is being protected from spambots. You need JavaScript enabled to view it.

 

 

OBJECTIVE: The aim of the study was to assess omega 3/6 fatty acids (eye q) in attention deficit hyperactivity disorder (ADHD).

 

METHOD: The study included a randomized, 3-month, omega 3/6 placebo-controlled, one-way crossover trial with 75 children and adolescents (8-18 years), followed by 3 months with omega 3/6 for all. Investigator-rated ADHD Rating Scale-IV and Clinical Global Impression (CGI) scale were outcome measures.

 

RESULTS: A majority did not respond to omega 3/6 treatment. However, a subgroup of 26% responded with more than 25% reduction of ADHD symptoms and a drop of CGI scores to the near-normal range. After 6 months, 47% of all showed such improvement. Responders tended to have ADHD inattentive subtype and comorbid neurodevelopmental disorders.

 

CONCLUSION: A subgroup of children and adolescents with ADHD, characterized by inattention and associated neurodevelopmental disorders, treated with omega 3/6 fatty acids for 6 months responded with meaningful reduction of ADHD symptoms.

 

PMID: 18448859 [PubMed - indexed for MEDLINE]

 


 

 

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