Potential of rosemary oil to be used in drug-resistant infections.

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Research - Candida & Gut Dysbiosis Research

Altern Ther Health Med. 2007 Sep-Oct;13(5):54-9.

Potential of rosemary oil to be used in drug-resistant infections.

Luqman S, Dwivedi GR, Darokar MP, Kalra A, Khanuja SP.

Genetic Resources and Biotechnology Division, Central Institute of Medicinal and Aromatic Plants (Council of Scientific and Industrial Research), Lucknow, India.

OBJECTIVE: To evaluate the antimicrobial activity potential of the essential oil of rosemary specifically for its efficacy against the drug-resistant mutants of Mycobacterium smegmatis, Escherichia coli, and Candida albicans. METHOD: Antibacterial, antifungal, and drug resistance-modifying activity was evaluated both qualitatively and quantitatively following disc diffusion and broth dilution assay procedures.

RESULTS: The rosemary essential oil was found to be more active against the gram-positive pathogenic bacteria except E. faecalis and drug-resistant mutants of E. coli, compared to gram-negative bacteria. Similarly, it was found to be more active toward nonfilamentous, filamentous, dermatophytic pathogenic fungi and drug-resistant mutants of Candida albicans.

CONCLUSION: Our findings suggest that characterization and isolation of the active compound(s) from the rosemary oil may be useful in counteracting gram-positive bacterial, fungal, and drug-resistant infections.

PMID: 17900043 [PubMed - in process]