J Clin Pathol. 2009 Oct 14. [Epub ahead of print]
Acute enterovirus infection followed by myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and viral persistence.
Chia JK, Chia AY, Voeller M, Lee TM, Chang R. EV Med Research, United States;
A number of infections have been associated with myalgia encephalomyelitis/chronic fatigue syndrome (ME/CFS). Often occurring in epidemics, enteroviruses are significant causes of respiratory, gastrointestinal infections, non-specific flu-like illnesses, and many disseminated infections. It has been difficult to demonstrate causality for chronic diseases without having well-documented cases of acute enterovirus infections. In this report, we described 3 patients presenting with acute enterovirus infections, which were followed by ME/CFS, and the persistent viral infections were demonstrated by finding enterovirus VP1 protein and RNA in the stomach.
PMID: 19828908 [PubMed - as supplied by publisher]