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Mold Illness Information & Products

Brain dysfunction in multiple chemical sensitivity

 

 

 

 

J Neurol Sci. 2009 Oct 2. [Epub ahead of print]

 

Brain dysfunction in multiple chemical sensitivity.

 

Orriols R, Costa R, Cuberas G, Jacas C, Castell J, Sunyer J. Servei de Pneumologia, Hospital Universitari Vall d' Hebron, Barcelona, Catalonia, Spain; CIBER Enfermedades Respiratorias (CIBERES), Spain.

 

 

Aims & Methods: Multiple Chemical Sensitivity (MCS) is a chronic acquired disorder of unknown pathogenesis. The aim of this study was to ascertain whether MCS patients present brain single photon emission computed tomography (SPECT) and psychometric scale changes after a chemical challenge. This procedure was performed with chemical products at non-toxic concentrations in 8 patients diagnosed with MCS and in their healthy controls.

 

Results: In comparison to controls, cases presented basal brain SPECT hypoperfusion in small cortical areas of the right parietal and both temporal and fronto-orbital lobes. After chemical challenge, cases showed hypoperfusion in the olfactory, right and left hippocampus, right parahippocampus, right amygdala, right thalamus, right and left Rolandic and right temporal cortex regions(p

 

Conclusions: Chemical exposure caused neurocognitive impairment, and SPECT brain dysfunction particularly in odor-processing areas, thereby suggesting a neurogenic origin of MCS.

 

PMID: 19801154 [PubMed - as supplied by publisher]

 

 

 

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  • Has there been any further study done on this subject? This is also most interesting to me...I have also tested very high for particularly lead and mercury, lesser amounts for many other metals. Chelation has brought the levels down somewhat, but am still having lots of symptoms. I too would love to know more about this

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  • this is very interesting to me as I am heavy metal toxic by as many as twelve different metals such as mercury, lead,nickel,zinc----. I am receiving chealation therapy but have not been diagnosed as MCS, yet I have not been able to return to work as I become ill upon entering the plant subsequently I am fighting my employer for benefits, but the thing is that i am having trouble with my brain and I believe it to be the cause of my toxicty and a sensitivity to ZINC THAT IS THE CAUSE AND AM TRYING TO FIND ALL THE RESEARCH I CAN SO THIS IS VERY INTERESTING AND I WOULD LIKE TO KNOW MORE.

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  • This is fantastic. These results confirm that those suffering from multiple chemical sensitivity (MCS) have reduced blood flow to specific areas of the brain both chronically, and to an increased degree after chemical exposure, when compared with healthy individuals. It is also important to note the particular regions affected such as the amygdalar which is the subconcious emotional control centre of the brain involved with the stress response for example. Dysfunction here can offer and explanation for why MCS patients often experience psychological symptoms (depression, anxiety etc) and the condition is dismissed as psychological. Yes, psychological symptoms maybe present but only because as the result of brain injury caused by and exacerbated by chemical exposures.

    It must be noted that this is only a very small study so unfortunately won't hold much weight in swaying opinions in the medical community but if the same study was repeated with larger numbers of MCS patients it certainly would. We all need to do whatever we can to make this happen ;)

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