Nystatin is a polyene type anti-fungal drug which is used for the treatment of infections with yeasts, fungi and molds. It is particularly effective against Candida species such as Candida albicans.

Nystatin works by interfering with the cell membranes of yeast and fungi. It binds to a substance called ergosterol, which is an essential component of fungal cell membranes. As a result the cell membranes rupture. Nystatin therefore works by essentially punching holes in yeast and fungal cells. As a result unwanted substances flow into the cell and essential constituents leak out, killing the cell and treating the infection.

Nystatin is not absorbed into the bloodstream through the intestines so is ideally suited for the treatment of Candida infections of the digestive tract, from the mouth and throat, down to the intestines where Candida overgrowth may occur (e.g. following antibiotic therapy).

Dr. William Crook in his book 'The Yeast Connection' advises that patients take half of their nystatin dose in powder/oral suspension form and half in tablet form. He explains that the powder best treats infections in the mouth and throat while more of the drug is likely to reach infections in the intestines when taken as tablets.

Please note: Nystatin is a prescription medication that should only be used under the supervision of your doctor. See side-effects.