Martin Pall is Professor of Biochemistry and Basic Medical Sciences at Washington State University. He has been investigating the causes of unexplained illnesses including chronic fatigue syndrome (ME/CFS), fibromyalgia, and multiple chemical sensitivity (MCS) for the past decade.
As a result of his research, Professor Pall has developed a comprehensive theory explaining how these illnesses develop and this has naturally led to proposed treatments to combat the underlying disease process. The majority of the recommended treatments are widely available nutritional and herbal supplements meaning that patients can implement the treatment themselves if they choose.
Professor Pall's hypothesis is that a variety of short-term stressors can trigger an increase in the levels of nitric oxide (NO) in the body and that this is the root cause of the symptoms associated with these illnesses.
He explains that the following can act as stressors triggering the increased NO:
> Viral, bacterial and protozoan infections
> Physical trauma (most commonly to the head and neck but also including physical trauma to other regions of the body).
> Chemical exposure to such chemicals as volatile organic solvents or such pesticides as organophosphorus/carbamates, organochlorine pesticides or pyrethroid pesticides.
> Carbon monoxide exposure
> Severe psychological stress
> Mold toxins
Usually an individual will recover when such short-term stressors are removed but in some people Professor Pall hypothesizes, a vicious cycle of elevated NO is initiated which maintains the illness.
As a consequence of elavted NO there is an increase in free radicals such as peroxynitrite which can damage tissues and cause dysfunction of cells and metabolic processes throughout the body.
Professor Pall therefore recommends individuals suffering from these illnesses should be treated with substances which decrease levels of NO and free radicals in the body. Most of these are natural antioxidant supplements.
A number of high profile healthcare professionals are using Professor Pall's treatment protocol to treat patients with unexplained chronic illnesses with reportedly high levels of success.
To learn more about Professor Pall's theory and treatment protocol please see the following:
Article - The No! Oh Noo! Theory and Suggestions for Treatment
Book - Explaining Unexplained Illnesses: Disease Paradigm for Chronic Fatigue Syndrome, Multiple Chemical Sensitivity, Fibromyalgia, Post-Traumatic Stress Disorder, and Gulf War Syndrome.