Hi,
Neither of these tests is specific to food allergies/sensitivities but they will still provide useful information.
While an inflammatory IgE (allergic) reaction with subsequent histamine release could contribute to both adrenal fatigue and increased intestinal permeability (leaky gut syndrome) it is certainly not the only, or even major, cause.
Adrenal fatigue can come about of any persistent stress that is placed on the body. This stress can take the form of psychological stress, chronic infection or illness, nutritional deficiencies, allergies, chronic exposure to chemicals or molds, gut dysbiosis (e.g. Candida overgrowth) and leaky gut syndrome. These are just some common examples but ANY \"stress\" can be the cause.
Many factors can increase the permeability of the intestinal mucosa. It shouldn't come as too much of a surprise to find that many are the same as those which contribute to adrenal fatigue. Gut dysbiosis and food allergies/sensitivities would be high on the list. Use of alcohol and other drugs known to increase intestinal permeability such as non-steroidal anti-inflammatory drugs (NSAIDS) (e.g ibuprofen) would also be up there. Deficiencies of nutrients vital for intestinal barrier function could also be pivotal - these nutrients include zinc, vitamin A, the amino acid l-glutamine, and
essential fatty acids (EFAs). There is also a strong connection to psychological stress that may not be immediately obvious. When we are stressed the fight-or-flight response is activated and the adrenal glands release adrenaline, cortisol and other hormones. One effect of these hormones is to effectively shut down digestion and divert blood supply away from the GI tract to the skeletal muscles. Chronic stress therefore leaves the intestines starved of blood, oxygen and nutrients so their health suffers and they become more permeable to toxins, allergens, and microogranisms.
Doing the ASI and intestinal permeability test will tell you if you have problems in these areas that may be contributing to your symptoms but will not tell you the cause. For this you need to be your own detective or work with a health care professional to determine the factors contributing in your individual case.<br /><br />Post edited by: Maff, at: 2009/11/17 20:06