Review Detail

 
Amitriptyline
Antidepressants
Written by Maff     December 16, 2008    
I used low dose amitriptyline (10mg) as a sleep aid for sleep problems associated with chronic fatigue syndrome (ME/CFS). I found it helped with getting to sleep. It basically knocked me out in a way that felt like a general anaesthetic.

That would have been fine but the next day I felt extremely drowsy and wobbly on my feet and was basically unable to function. It was like I was walking around like a zombie. My memory was also affected.

It could be that I was particularly sensitive but 10mg is already a low dose (much higher doses of 50mg+ are used for depression treatment) so there was little point tinkering with dosages.

Not a good experience for me. In terms of medications the benzodiazepines such as diazepam/Valium help with sleep without the next day side-effects and I have also found melatonin and phosphatidylserine supplements highly effective.

Overall rating 
 
3.4
Perceived Effectiveness  
 
4.0
Lack of side effects (tolerability)  
 
2.0
Ease of use  
 
5.0
Value for money  
 
2.0
Would you recommend? 
 
4.0
Maff Reviewed by Maff December 16, 2008
Last updated: July 29, 2009
#1 Reviewer  -   View all my reviews (107)

Caused severe drowsiness

I used low dose amitriptyline (10mg) as a sleep aid for sleep problems associated with chronic fatigue syndrome (ME/CFS). I found it helped with getting to sleep. It basically knocked me out in a way that felt like a general anaesthetic.

That would have been fine but the next day I felt extremely drowsy and wobbly on my feet and was basically unable to function. It was like I was walking around like a zombie. My memory was also affected.

It could be that I was particularly sensitive but 10mg is already a low dose (much higher doses of 50mg+ are used for depression treatment) so there was little point tinkering with dosages.

Not a good experience for me. In terms of medications the benzodiazepines such as diazepam/Valium help with sleep without the next day side-effects and I have also found melatonin and phosphatidylserine supplements highly effective.

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