(1) On April 25, 2001 James J Bradstreet, MD, F.A.A.F.P gave testimony before the US House of Representatives, Committee on Government Reform recalling his own experiences with an autistic son as well as providing a broad review of issues surrounding childhood autism. In a written supplement to the oral presentation, which can be accessed on the website: http://www.gnd.org/Testimony/Congressional.htm, Dr. Bradstreet provided current statistics on autism, pages 3-7.
(3) NIH/ACC 2001 Conference: Potential Cellular and Molecular mechanisms in autism and Related disorders Sponsored by NICHD and NIEHS, Co-Sponsored by NIMH, NINDS, and NIDCD, September 6-7, 2001, Bethesda, Maryland. (Having personally had the privilege of attending the meeting, there were very excellent presentations having to do with neuro-anatomical findings as well as genetics of autism, areas constituting basic science for the field. A portion of the meeting was also devoted to the possible roles of pesticides and other neurotoxicants in causing autism, but even these were of an academic nature. Clinical studies of potential value in either the prevention or treatment of autism were notable by their absence.)
(4) Annual hearings specifically dealing with questions about vaccine safety have been taking place in the U.S, House of Representatives since 1999. This is only one of many indications of growing public and professional concern on this issue.
(5) Edelson SB & DS Cantor, Autism: xenobiotic influences, Toxicology and Industrial Health, 1998; 14(4):553-563. (This study, which appears to be the first of its kind, points out that the breathing of toxic, chemical-laden air in sick buildings by women during their pregnancies may be a contributing cause of brain damage to the fetus and a common factor in the rising incidence of childhood autism).
(6) Among the many works dealing with the adverse health consequences of "fast foods," which form an increasing pattern in the diets of American children, two books are recommended here: Nourishing Traditions, by Sally Fallon with Pat Connolly and Mary G Enig, Ph.D., ProMotion Publishing, San Diego, 1995 and Special Diets for Special Kids, by Lisa Lewis, Ph.D., Future Horizons, Arlington, Texas, 1998.
(7) No reference is needed here - the overuse of antibiotics in medicine and the food industry is now universally recognized and is being taught at leading medical centers.
(8) Stratton KR, CJ Howe and RB Johnston, Jr., Editors, Adverse Events Associated with Childhood Vaccines; Evidence Bearing on Causality, Institute of Medicine, National Academy Press, Washington D.C., 1994, pp 211-236.
(9) Wakefield AJ & S Montgomery, Measles, mumps, rubella vaccine: through a glass darkly, Adv Drug React Toxicol Rev, January, 2001; 19(3):1-19.
(10) Hurley DR, DW Vere, A P Fletcher, Referee 1, 2, 3, & 4, Adverse Drug React Toxicol Rev, 2001; 19(4):1-2.
(11) Eibl M et al, Abnormal T-lymphocyte subpopulations in healthy subjects after tetanus booster immunization, (letter), NEJM, 1984; 310(3):198-199.
(12) American Academy of Environmental Medicine, with headquarters at American Financial Center, 7701 East Kellogg, Suite 625, Wichita, Kansas 67207-1705, phone (316) 684-5500, Fax (316) 684-5709.
(13) Pesticides in the Diets of Infants and Children, National Research Counsel, National Academy Press, Washington D.C., 1993. (Although this book deals with foods rather than air, it provides further evidence of concern in leading scientific circles about the potential impact of toxic chemicals on human health).
(14) Neurotoxicity, Identifying and Controlling Poisons of the Nervous System, Superintendent of Documents, Government Printing Office, Washington D.C., GPO Stock # 052-003-01184-1, April, 1990.
(15) Environmental Hazards in Your School, A Resource Handbook, US Environmental Protection Agency, Washington D.C., Publication # 201-2001, October, 1990.
(16) The Healthy School Handbook, Norma L Miller, Ed.D., Editor, a National Education Association professional Library Publication, National Education Association, Washington D.C., 1995.
(17) Multiple Chemical Sensitivities at Work, Produced by The Labor Institute, NYC, 853 Broadway, Room 2014, New York, NY 10003, 1993 (funded by a grant from the New York State Department of labor, Occupational Safety and Health Training and Education Program).
(18) Multiple Chemical Sensitivities, National Research Counsel, National Academy Press, Washington D.C., 1989.
(19) Ibid, page 2.
(20) Callender TJ, L Morrow, & K Subramanian, Evaluation of chronic neurological sequelae after acute pesticide exposure using SPECT brain scans, J Toxicol Environm Health, 1994; 41:275-284.
(21) Morrow LA, CM Ryan, & M Hodgson, Cacosmia and neurobehavioral dysfunction associated with occupational exposure to mixtures of organic solvents, Am J Psychiatry, 1988; 145:1442-1445.
(22) Morrow LA, MJ Hodgson, & N Robin, Assessment of attention and memory efficiency in persons with solvent neurotoxicity, Neuropsychologia, 1992; 30(10):911-922.
(23) Morrow LA, CM Ryan, MJ Hodgson, & N Robin, Risk factors associated with persistence of neuropsychological deficits in persons with organic solvent exposure, J Nervous & Mental Dis, 1991; 179:540-545.
(24) Michelle Conlin, Is your office killing you?, Business Week, June 5, 2000, pages 114-125. (In this article the authoress stated, "Experts predict that the 5% to 10% of the population that is allergic to chemicals will grow to 60% by 2020." She did not state where she obtained these figures, but a general observation of the American scene tends to support their validity.)
(25) Simon TR, DC Hickey, CE Fincher et al, Single photon emission computed tomography of the brain in patients with chemical sensitivity, Toxicol Industr Health, 1994, 10(4/5):573-577.
(26) Hannan KL, DE Berg, W Baumzweiger, HH Harrison et al, Activation of the coagulation system in Gulf War Illness: a potential pathophysiologic link with chronic fatigue syndrome - a laboratory approach to diagnosis, Blood Coagulation and Fibrinolysis, 2000; 11:673-678.
(27) Buist RA, Chronic fatigue and chemical overload, Intern Clin Nutrition Rev, Oct., 1988, 8(4):173-175.
(28) Beaune P et al, Autoantibodies against cytochrome P-450; role in human disease, Adv Pharmacol, 1994; 30:199-245. (Note: detoxification in the body is centered around two enzyme systems. The first is the P-450 system which, by a process of oxidization, converts the lipid-soluble state of volatile organic compounds into a more water soluble form, in which form they are more readily excreted by the kidneys. There is a price to pay, in that the water-soluble forms of VOCs may be more toxic than their parent compounds. In health the second phase of detoxification, that of conjugation, takes place immediately to neutralize the toxicity in which process the toxic product is combined with various natural substances in the body, predominantly glutathione. In many instances in chemical sensitivity there appears to be a relative deficiency of the conjugation enzyme activity which results in an accumulation of the more toxic products of phase I oxidation.
(29) Chemical Sensitivity, Volumes I - IV, William J. Rea, M.D., Lewis Publishers, Boca Raton, FL , Vol I, 1992, Vol II, 1994, Vol III, 1995, Vol IV, 1997.
(30) The Case for Preconception Care of Men and Women, Margaret and Arthur Wynn, AB Academic Publishers, PO Box 42, Bicester, Oxon, 0X6 7NW England 1991.
(31) Among the parents with autistic children, a significant portion of these parents believe that their children have been damaged by vaccines. A common story in such instances is that the child was developing normally into his or her second year, was beginning to speak a few words, was affectionate with parents and playful with siblings until a vaccination took place, after which the child lost all speech and regressed into a world of its own, no longer responding to parents or playmates.
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