Harefuah. 2006 Jul;145(7):486-8, 551.
Allergic contact dermatitis to cocamidopropyl betaine among Israeli patients with cosmetic allergy.
Raz O, Slodownik D, Ingber A. Department of Dermatology, Hadassah University Hospital, Faculty of Medicine, Jerusalem.
INTRODUCTION: Cocamidopropyl betaine (CAPB) is an amphoteric surfactant commonly used in rinse-off cosmetic products. There is still a debate concerning the actual allergen in CAPB. OBJECTIVE: To evaluate the prevalence of CAPB allergy and its characteristics among Israeli patients. METHODS: A hundred consecutive patients with suspected cosmetic allergy were patch tested. They underwent standard and cosmetic series patch tests. RESULTS: Six patients, all females, were allergic to CAPB. Relevance rate was 66%. No significant characteristics were found among allergic patients. CONCLUSION: The rate of CAPB allergy is similar to the prevalence worldwide. CAPB became one of the leading causes of cosmetic allergy.
PMID: 16900735 [PubMed - in process]