Drug intolerance in patients with idiopathic environmental intolerance syndrome

Int J Clin Pract. 2006 Jun 19; [Epub ahead of print]

Drug intolerance in patients with idiopathic environmental intolerance syndrome.

Niedoszytko M, Chelminska M, Buss T, Roik E, Jassem E.

Department of Allergology, Department of Internal Diseases, Endocrinology and Hemostatic Disorders, Department of Palliative Medicine, Medical University of Gdansk, Gdansk, Poland.

The increasing rate of the idiopathic environmental intolerance (IEI) has been observed for the last decade. The aim of this report was to analyse the allergic component of the disease in particular relation to drug intolerance. Six patients with diagnosed IEI showed a positive skin test reaction to several commonly used antibiotics, nonsteroidal anti-inflammatory drugs, myorelaxants, verapamil, etc. In three cases, the thorough diagnosis of sensitivity to anaesthetic agents enabled to perform necessary surgical treatment, in others - facilitated the proper treatment of headaches and hypertension. Symptoms related to allergy contributed to the deterioration of IEI. Thus, a consultation of IEI patients by an allergologist seems to be of a substantial importance.

PMID: 16787439 [PubMed - as supplied by publisher]