BMC Musculoskelet Disord. 2009 Dec 21;10(1):162. [Epub ahead of print]
Cognitive impairment in patients with Fibromyalgia syndrome as assessed by the Mini-Mental State Examination.
Rodriguez-Andreu J, Ibanez-Bosch R, Portero-Vazquez A, Masramon X, Rejas J, Galvez R.
BACKGROUND: This study evaluated the frequency of cognitive impairment in patients with Fibromyalgia syndrome (FMS) using the Mini Mental State Examination (MMSE).
METHODS: We analyzed baseline data from all 46 patients with FMS and 92 age- and sex-matched controls per diagnosis of neuropathic (NeP) or mixed pain (MP) selected from a larger prospective study.
RESULTS: FMS had a slight but statistically significant lower score in the adjusted MMSE score (26.9; 95% CI 26.7-27.1) than either NeP (27.3; 95% CI 27.2-27.4) or MP (27.3; 27.2-27.5). The percentage of patients with congnitive impairment (adjusted MMSE [less than or equal to] 26) was numerically higher in FMS (15%; 95% CI 6.3-29) compared with NeP (5%; 95% CI 1.8-12.2) or MP (5%; 95% CI 1.8-12.2) and higher than in the same age stratum of the general population (0.05%).
CONCLUSIONS: Compared with the population reference value, patients with FMS showed high frequency of cognitive impairment.
PMID: 20025750 [PubMed - as supplied by publisher]