Social Links

Follow on Facebook Follow on TwitterFollow EiR on PinterestFollow EiR on Instagram

Xpert Access


Login To Get Involved!

Forgot your username?

Forgot your password?


Join Us At EiR Now!

DNRS Roof Banner


DNRS Interactive DVD Series & Seminars

Change over time of bowel habit in irritable bowel syndrome





Aliment Pharmacol Ther. 2007 Jan 8; [Epub ahead of print]


Change over time of bowel habit in irritable bowel syndrome: a prospective, observational, 1-year follow-up study (RITMO study).


Garrigues V, Mearin F, Badia X, Balboa A, Benavent J, Caballero A, Dominguez E, Diaz-Rubio M, Roset M, Figueras M, Cucala M; RITMO GROUP. Digestive Medicine Department, Hospital Universitari La Fe, Valencia, Spain.


Background Evolution of bowel habit in irritable bowel syndrome (IBS) is not well known. Aim To evaluate the change over time of bowel habit in IBS patients followed-up during 1 year. Methods Five hundred and seventeen patients with IBS were prospectively included in an observational study with five evaluations over a 1-year period. Symptoms were recorded daily in diary cards during four 4-week periods along the study. Bristol Stool Scale (BSS) was used to define bowel habit. Results Four-hundred patients completed the study. Rome II showed low-moderate agreement (42%) with BSS to define bowel habit. Frequency of constipation and diarrhoea showed little changes throughout the study. Over 50% of the patients had the same bowel habit when each diary was compared with the next one. A third of patients maintained the same habit throughout the study. Most changes occurred from/to mixed or unsubtyped IBS. Only 14% of cases changed from constipation to diarrhoea or vice versa. This change was associated to female gender (OR: 2.65). Conclusions The frequency of constipation and diarrhoea remains relatively stable over time. Changes in IBS subtypes are common, but changes between constipation and diarrhoea are rare. Alternating IBS is more frequent in women.


PMID: 17217445 [PubMed - as supplied by publisher]










Related Articles:


Home Testing & Sanitizer:







  • No comments found

Leave your comments

Post comment as a guest

0 Character restriction
Your text should be more than 25 characters
Your comments are subjected to administrator's moderation.
terms and condition.

Adsense Responsive BottomBanner