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Mindfulness for irritable bowel syndrome: Protocol development for a controlled clinical trial





BMC Complement Altern Med. 2009 Jul 28;9(1):24. [Epub ahead of print]


Mindfulness for irritable bowel syndrome: Protocol development for a controlled clinical trial.


Gaylord SA, Whitehead WE, Coble R, Faurot KR, Palsson O, Garland EL, Frey W, Mann JD.



BACKGROUND: Irritable bowel syndrome (IBS), a functional bowel disorder with symptoms of abdominal pain and disturbed defecation experienced by 10% of U.S. adults, results in significant disability, impaired quality of life, and health-care burden. Conventional medical care focusing on pharmacological approaches, diet, and lifestyle management has been partially effective in controlling symptoms. Behavioral treatments, such as cognitive-behavioral therapy and hypnosis, are promising. This paper describes an on-going feasibility study to assess the efficacy of mindfulness training, a behavioral treatment involving directing and sustaining attention to present-moment experience, for the treatment of IBS.


METHODS: The study design involves randomization of adult women with IBS according to Rome II criteria, to either an eight-week mindfulness training group (based on a Mindfulness-based Stress Reduction format) or a previously validated IBS social-support group as an attention-control condition. The primary hypothesis is that, compared to Support Group participants, those in the Mindfulness Program will demonstrate significant improvement in IBS symptoms as measured by the IBS Symptom Severity Scale [1].


RESULTS: 214 individuals have been screened for eligibility, of whom 148 were eligible for the study. Of those, 87 were enrolled, with 21 withdrawing after having given consent. 66 have completed or are in the process of completing the interventions.


CONCLUSION: It is feasible to undertake a rigorous randomized clinical trial of mindfulness training for people with IBS, using a standardized MBSR protocol adapted for those experiencing IBS, compared to a control social-support group previously utilized in IBS studies. Trial Registration: Clinical Identifier: NCT00680693.


PMID: 19638214 [PubMed - as supplied by publisher]










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  • It is great to hear that a randomised clinical trial has been designed to test the effectiveness of mindfullness techniques in irritable bowel syndrome (IBS). The gut-brain connection represents a powerful two-way communication network. As such, stress of any kind strongly impacts digestive function. Mindfullness is a useful tool for quitening the mind, reducing stress, and improving coping skills that may well benefit the symptoms of IBS. I have personally found mindfullness and meditation practiced daily to help with many symptoms of my illness (CFS, IBS etc).

    See this blog entry - Mindfullness-Based Cognitive Behavioural Therapy

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