Social Links

Follow on Facebook Follow on TwitterFollow EiR on PinterestFollow EiR on Instagram

Xpert Access

×

Login To Get Involved!


Forgot your username?


Forgot your password?

×

Join Us At EiR Now!

DNRS Roof Banner

 

DNRS Interactive DVD Series & Seminars

T cells and colonic subepithelial myofibroblasts: what are they doing in mucosal inflammation

 

 

 

 

J Gastroenterol. 2007 Jan;42 Suppl 17:29-33.

 

Interaction between interleukin-17-producing CD4(+) T cells and colonic subepithelial myofibroblasts: what are they doing in mucosal inflammation?

 

Andoh A, Ogawa A, Bamba S, Fujiyama Y. Department of Internal Medicine, Shiga University of Medical Science, Seta-Tukinowa, Otsu, 520-2192, Japan.

 

Recent studies have shown alterations and activations in the mucosal immune system in patients with irritable bowel syndrome (IBS) as well as in those with inflammatory bowel disease (IBD). As one of effectors of mucosal inflammation, a new lineage of effector CD4(+) T cells characterized by production of interleukin (IL)-17, the T-helper (Th)-17 lineage, was recently described. Th-17 cells are developmentally and functionally distinct from Th1 and Th2 cells. Here, we discuss the recent concept of low-grade inflammation as a factor associated with the pathophysiology of IBS. Furthermore, based on the data from our laboratory, interaction between Th-17 cells and colonic subepithelial myofibroblasts may play an important role in the pathophysiology of IBS and IBD.

 

PMID: 17238023 [PubMed - in process]

 

Full Article Available Online

 

 

 

{mosgoogle}

 

{mos_sb_discuss:11}

 


 

 

Related Articles:

 

Home Testing & Sanitizer:
 

 

 

 

 

ADVERTISEMENT

 

  • No comments found

Leave your comments

Post comment as a guest

0 Character restriction
Your text should be more than 25 characters
Your comments are subjected to administrator's moderation.
terms and condition.

Adsense Responsive BottomBanner