Acta Clin Croat. 2009 Mar;48(1):65-73.

 

New concepts of neural regulation in human nasal mucosa.

 

Baraniuk JN, Merck SJ. Division of Rheumatology, Immunology and Allergy, Georgetown University, Washington, DC 20007-2197, USA. This email address is being protected from spambots. You need JavaScript enabled to view it.

 

 

Nasal mucosa is innervated by multiple subsets of nociceptive, parasympathetic and sympathetic nerves. These play carefully coordinated roles in regulating glandular, vascular and other processes. These functions are vital for cleaning and humidifying ambient air before it is inhaled into the lungs. The recent recognition of distinct classes of nociceptive nerves with unique patterns of sensory receptors that include seven transmembrane G-protein coupled receptors, new families of transient receptor potential and voltage and calcium gated ion channels, and combinations of neurotransmitters that can be modulated during inflammation by neurotrophic factors has revolutionized our understanding of the complexity and subtlety of nasal innervation. These findings may provide a rational basis for responses to air temperature changes, culinary and botanical odorants ("aromatherapy"), and inhaled irritants in conditions as diverse as idiopathic nonallergic rhinitis, occupational rhinitis, hyposmia, and multiple chemical sensitivity.

 

PMID: 19623876 [PubMed - in process]

 

 

 

{mosgoogle}

 

{mos_sb_discuss:10}

 


 

Please Help Support EiR with a Positive Google Review!

Review 'The Environmental Illness Resource' (EiR) on Google

 

If you like EiR and / or enoyed this content; please help us keep going by leaving a Positive Google Review:
Review EiR on Google NOW!

P.S. This is entirely secure, we collect no data other than what is freely available from Google and you can remain anonymous!

 


Related Articles:

 

Mold Testing & Sanitizer:

 

 

 

 

ADVERTISEMENT