Results of CDSA before and after fecal transplant

Discussion started by True 9 years ago

This person just posted their CDSA report,  before and after transplant

 

http://www.walkingfilm.com/2011/07/

 

I wish he would post before and after description of his health. Seems it did get rid of some negative bacteria.

 

You need to be a member of this group before you can participate in this discussion.
Maff
Maff
Seems a bit mad doing a faecal implant and then hitting the alcohol which is known to be negatively impact gut microflora as well as increasing intestinal permeability (leaky gut)! I don't think we can really use this guy as a valid example of the pros and cons of faecal bacteriotherapy as he doesn't seem to have taken other factors into account at all well!
9 years ago
True
True
i found his diary on the right hand side..www.walkingfilm.com/hpi-fecal-transplant-cont/… recommend alcohol after a transplant.
9 years ago
True
True
Is there a thread that discusses the implications of particular results of the CDSA in this forum? thanks
9 years ago
Maff
Maff
Mike - I'm not a microbiologist either so I can't say anything with any authority. Most of the results that come up when you Google 'haemolytic escherichia coli' refer to its effects in animals where it appears to cause diarrhoea. I did find this paper that reports on an in vitro experiment that found many strains of haemolytic E. coli produce a toxin that is toxic to human white blood cells - onlinelibrary.wiley.com/doi/10.1111/j.1699-0463.1988.tb05312.x/… general I think the bacteria labelled as NP by Genova are those that aren't especially harmful but the human host gets no benefit from them being there. They are taking up space that could be inhabited by the beneficial bacteria that do provide benefit. So better those 'Additional Bacteria' were not present. I assume the lab would label any known pathogenic form of E. coli found in a stool sample as such on the report.

I don't think pathogenic bacteria would necessarily be better able to implant and colonise. Every type of bacteria does what it can to survive and that includes developing ways of successfully implanting in a new environment. I am cautiously taking the fact those E. coli strains that appeared after this guys HPI as a positive. It would obviously have been more heartening to see the Lactobacilli go up to 3+/4+ though!
9 years ago
MikeH
MikeH
Yep I was refering to the haemolytic and mucoid E. Coli. Didn't know that the E coli. listed in the additional section were bad guys (it does say NP - Non-pathogen - next to them) but i'm in way over my head and just speculating with any analysis I make.

Are those E coli strains bad then Maff? Can we see it as a positive that they were able to implant so well post FT or is that a characterisitic of pathogenic bacteria?
9 years ago
Maff
Maff
True - I think Mike was referring to the haemolytic and mucoid E. coli that were not present in the 'Additional Bacteria' section of his before CDSA but were 4+ and 3+ in the After CDSA. Not good! Mike, I also spotted that yeast had appeared at 1+ which is a concern. We have to remember that this test is not 100% reliable however so I'm sure if you tested a couple of months apart without doing a thing you could have yeast show up as 0 then 1+. The nasty E. coli sp. look a lot more conclusive with those high numbers.

I also want to get my beneficial E. coli up True. On a previous test around 10 years ago I had low Lactobacillus and E. coli. It was only my Bifidobacteria that were normal in the beneficial bacteria section. I have a lot of problems with sleep too - although there are a lot of factors I know to be involved in my case at least!
9 years ago
True
True
I just re-checked the befores and his e-coli was already at +4 before transplant. Though I still have hope. He mentioned he was hoping to get rid of the b.hominis and it was reduced to "rare" from "many"
9 years ago
True
True
I didnt notice the e.coli increase. I am glad you mentioned that mike.

My CDSA showed zero e.coli. I am hoping to increase my e.coli with the transplant as I have read that lack of e.coli can be the cause of insomnia which I have suffered from since my c-section/ three day intravenous antibiotic stint. Makes me very hopeful indeed.
9 years ago
Maff
Maff
Hey True,

Thanks so much for posting this - very interesting. It looks like some of this guys markers such as stool pH and SCFAs moved more towards the middle of the normal range and there was clearly a reduction in some of the undesirable microbes he had. I'm sure he must have been disappointed that there was no improvement in his 0 for Lactobacillus sp.

I agree it would have been good if he provided some commentary on any changes in symptoms and whether he used any antiobiotics or other treatments along with the faecal transplant or whether the changes seen were all due to the faecal transplant itself.
9 years ago
MikeH
MikeH
Thanks for the link. Not sure you could say that it got rid of his negative bacteria - perhaps he did some prep work pre-FT that could account for that. The new bacteria may well have had an affect on the existing population though. What I found really interesting is the e.coli strains that seem to have got well implanted which surely must have come from his donor. Looks like he picked up some yeast as well. I wonder if he had his donor tested beforehand?

Makes me think maybe I should shell out for tests before I start - got to get donor tested again post pathogen treatment. Food for thought.
9 years ago

Related Discussions