Antioxidants

Source Naturals SAMe -- 200 mg - 60 Enteric Coated Tablets

Manufacturer:
Source Naturals SAMe is a stable, bioavailable form of S-adensoyl-L-methionine. These tablets are enteric coated and blister packed to prevent breakdown and inactivation of the ingredients. Studies show that SAMe helps support a positive outlook. It is able to cross the blood-brain barrier, where it affects the synthesis and activation of various proteins, such as neurotransmitters. SAMe also plays a role in transmethylation. Transmethylation reactions affect the synthesis, activation, and metabolism of various biological molecules. Some compounds that SAMe methylates are phospholipids. This is a fundamental step in the mediation of cell to cell communication.

The Environmental Illness Resource:
Of most immediate benefit to environmental illness sufferers are the actions of SAMe on liver and brain function. Low glutathione levels and resulting oxidant stress are commonplace in environmental illnesses. SAMe, being a key component in it's production, has been shown to raise glutathione levels and reduce oxidative stress. Cognitive and mood symptoms are also invariably present to one degree or another in envionmental illnesses. SAMe acts to help these problems through a process called methylation which results in the production of important brain chemicals. It can thus relieve depression and other mental/emotional problems. Many, many studies have confirmed the effectiveness of SAMe supplements for both liver and brain problems.

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Life Extension N-Acetyl-Cysteine -- 600mg - 60 Capsules

Manufacturer:
L-cysteine is a conditionally essential amino acid, one of only three sulfur-containing amino acids, the others being taurine (which can be produced from L-cysteine) and L-methionine from which L-cysteine can be produced in the body by a multi-step process. Cysteine plays a role in the sulfation cycle, acting as a sulfur donor in phase II detoxification and as a methyl donor in the conversion of homocysteine to methionine. Cysteine also helps synthesize glutathione, one of the body’s most important natural detoxifiers. N-acetyl-cysteine is the acetylated form of L-cysteine, which is more efficiently absorbed and used.

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Life Extension Taurine -- 1000 mg - 50 Capsules

Manufacturer:
Taurine is a conditionally essential amino acid produced from cysteine by the body and found abundantly in the body, particularly throughout the excitable tissues of the central nervous system, where it is thought to have a regulating influence. However, taurine is deficient in many diets and may not be sufficiently produced by the body in certain disease states.

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Jarrow Formulas Acetyl L-Carnitine -- 250 mg - 120 Capsules

Manufacturer:
Acetyl L-Carnitine is a more bioavailable form of L-Carnitine and is involved in many metabolic functions. As an antioxidant, acetylcarnitine can protect neurons from damage caused by superoxide radicals. Acetylcarnitine is involved in other aspects of neuronal metabolism because its molecular structure resembles the neurotransmitter acetylcholine. Acetylcarnitine supplementation supports energy utilization by its effects on fatty acid metabolism in the mitochondria.
L-CarniPure® Acetyl L-Carnitine is manufactured by Lonza, the industry leader, offering the finest L-Carnitine in the world.

The Environmental Illness Resource:
L-carnitine has a range of actions that may be of particular benefit to environmental illness sufferers. The acetyl form is seen as the most bioactive and hence potent form. A major benefit of L-carnitine supplementation may be increased energy levels due to its involvement with the metabolism of protein, carbohydrate and especially fats. Something we're sure all those with environmental illness would be glad of! Another major benefit is the fact that this amino acid supports the action of glutathione, the body's primary anti-oxidant. Glutathione has consistently been shown to be low in the whole range of environmental illnesses. Furthermore, L-carnitine may improve mood and memory through its action within the brain, reducing feelings of brain fog and those embarrassing and frustrating occassions when you can't remember the simplest things.

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Enzymatic Therapy Silybin Phytosome -- 120 mg - 60 UltraCaps

Manufacturer:
The patented Phytosome™ technology, which combines one part silybin (the most beneficial component of milk thistle extract) with two parts phosphatidylcholine, dramatically improves absorption. Research indicates Phytosomes are absorbed more effectively than non-Phytosome products. With this enhanced delivery, more of the key compounds get where they're needed most - to the cells in your body.

The Environmental Illness Resource:
Silymarin, from the Milk Thistle plant, is one of the most studied and utilized herbs for medicinal uses. There is a vast body of research showing it to be highly effective in treating the full spectrum of liver disorders from mild liver impairment to cirrhosis. It works by multiple mechanisms, both directly protecting liver cells and encouraging regeneration and by increasing levels of glutathione, the body's master antioxidant. Silymarin is actually made up of 3 different substances and silybin has been found to be by far the most active component. This supplement combines silybin with phosphatidylcholine (also very important for liver function) to both increase absorption and activity.

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Jarrow Formulas Alpha Lipoic Sustain with Biotin -- 300 mg - 60 Sustained Release Tabs

Manufacturer:
Alpha Lipoic Acid 300 is in a sustained release format to minimize gastric irritations and blood sugar fluctuations. Alpha Lipoic Acid is a disulfide molecule (containing two thiol groups). A thiol (or -SH) consists of a sulfur and a hydrogen atom. This unique antioxidant is both lipid and water soluble, a potent promoter of glutathione synthesis and cofactor in energy production, helping to regulate glucose metabolism. Jarrow Formulas Alpha Lipoic Acid is made in Italy. Biotin is added for optimum ALA activity.

The Environmental Illness Resource:
Alpha lipoic acid is often referred to as the 'universal antioxidant' due to the fact that it is both fat and water soluble. This means it can defend all parts of the body's cells from free radical damage rather than just the watery or fatty regions like most antioxidants. As well as being a particularly powerful antioxidant in its own right, directly neutralizing free radicals, alpha lipoic acid also plays a role in recycling other important antioxidants such as vitamins C and E, glutathione and Coenzyme Q10. This ALA formula from Jarrow is sustained release to improve activity and reduce potential side effects.

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Source Naturals PPC (polyenyl-phosphatidylcholine) -- 900 mg - 60 Softgels

Manufacturer:
Polyenylphosphatidylcholine (PPC) is pure phosphatidylcholine derived from soy. PPC contains no other phospholipids that may compete for absorption. Studies show PPC ingestion increases choline levels in the blood and the brain, and supports acetylcholine synthesis for proper neuronal and cell function.

Daily supplementation of PPC may support and maintain healthy brain and liver function; and gastric mucosal protection.

The Environmental Illness Resource:
Currently, along with SAMe, PPC appears to show the most promise of all nutrients tested for the treatment of the whole spectrum of liver disorders. This is borne out by the number of studies investigating its effects and the positive results that are being obtained. In a recent study investigating novel new treatments the investigators studied PPC in detail and found it to be highly effective at treating both cirrhosis and alcoholic hepatitis. They found the beneficial effects to be due to PPC's ability to oppose lipid peroxidation (damage to fats (including cell membranes) due to free radicals) and restore phospholipid levels thus regenerating damaged liver cells. Although relatively expensive, we highly recommend this supplement where moderate to severe liver impairment is suspected.

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