Carnitine
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Carnitine is an amino acid that is important for the metabolism of fats, specifically it transports fatty acids into the mitochondria where they can be used as fuel. Through this mechanism carnitine helps to reduce fatty build up in the liver and reduces the amounts of triglycerides in the blood thus reducing heart disease risk. It can be synthesised in the liver providing that sufficient amounts of methionine, lysine, iron and vitamins B1 and B6 are present. Carnitine is often recommended for those suffering from chronic fatigue syndrome (CFS) as a way of reducing fatigue and increasing energy levels. Supplements generally come in two forms - l-carnitine and acetyl-l-carnitine. It is suggested that acetyl-l-carnitine may help to maintain levels of the important neurotransmitter acetylcholine by donating an acetyl group.
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Editor reviews
I should explain that I have experienced this overstimulation from a lot of supplements that others have found very helpful. This is more than likely due to my low DHEA levels which fail to provide a balance to the stimulant effects of various "energy boosting" supplements.
I did find that carnitine supplements were very beneficial for my liver function which would be expected due to their anti-oxidant properties and ability to improve fatty acid metabolism within the liver.
From my experience carnitine is a very powerful supplement that may well benefit those suffering from fatigue related illnesses. I would recommend a trial but suggest starting at low doses and building up to see how you react to it.
| Overall rating | 7.2 | |
| Perceived Effectiveness | 7.0 | |
| Lack of side effects (tolerability) | 6.0 | |
| Ease of use | 9.0 | |
| Value for money | 7.0 | |
| Would you recommend? | 7.0 |
Reviewed by
Maff
September 28, 2007
Last updated: July 25, 2009
#1 Reviewer - View all my reviews (107)
Well worth a try for those suffering from fatigue
I've tried both l-carnitine and acetyl-l-carnitine and noticed definite effects from both. Having tried both at a dose of 500mg twice daily I found both gave a strong energy boost. Unfortunately, rather than a smooth boost in energy that would have enabled me to maintain activity throughout the day it all seemed to come in one big lump rather like a stimulant. As a result, at the end of the day I was actually left exhausted and also had trouble sleeping due to the overstimulation. In this respect I found that the acetyl version was stronger, perhaps due to increasing acetylcholine levels.
I should explain that I have experienced this overstimulation from a lot of supplements that others have found very helpful. This is more than likely due to my low DHEA levels which fail to provide a balance to the stimulant effects of various "energy boosting" supplements.
I did find that carnitine supplements were very beneficial for my liver function which would be expected due to their anti-oxidant properties and ability to improve fatty acid metabolism within the liver.
From my experience carnitine is a very powerful supplement that may well benefit those suffering from fatigue related illnesses. I would recommend a trial but suggest starting at low doses and building up to see how you react to it.
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